Negotiable
The date of payment from buyers deliver within days
Beijing
Long-term effective
2020-04-10 20:00
121
Company Profile
By certification [File Integrity]
Contact：ningqiangqixin(Mr.)
Email：
Telephone：
Phone：
Area：Beijing
Website：http://www.nqqxpharma.com/ http://ningqiangqixin.zthywj.com/
Active ingredients: Eucommia bark contains chlorogenic acid, eucommia gum, olivil, genipin, pectin, alkaloids, ketose, vitamin C and other ingredients. Eucommia ulmoides leaves contain 2-3% of chlorogenic acid, 14 kinds of lignans and ligninoglycosides, and the sugars linked to aglycon are glucopyranose .
Solubility: Eucommia extract chlorogenic acid 98 has good water solubility. Easily soluble in hot water, ethanol and acetone, high-purity chlorogenic acid can be completely dissolved. Very slightly soluble in ethyl acetate.
Source and Origin: Extracts from the leaves of Eucommia Ulmoides Oliver or Eucommia Ulmoides Oliver, distributed in Hunan, Hubei, Sichuan, Shaanxi and other places in China .
Use part : Leaf
Molecular formula：C16H18O9
Structure :
【Extraction and purification of chlorogenic acid】
1. Supercritical method: Supercritical CO2 is used as solvent to extract chlorogenic acid from medicinal materials. The method has a wide operating range and can extract effective ingredients in a targeted manner, while
Extraction and distillation are integrated, no solvent is required, no pollution, and the product has high purity. But the equipment is expensive and there are certain difficulties in industrial production.
2. Macroporous resin adsorption method: Macroporous resin adsorption is particularly suitable for purification and separation of water-soluble compounds. The method has large adsorption capacity, good selectivity, and is easy to solve
Suction, high mechanical strength, simple regeneration process, fast adsorption speed, simple operation, constant yield, stable product quality, low production cost, etc., and the adsorption method is only used
A small amount of solvent can elute the resin to achieve the purpose of concentration, but it takes a long time and it is difficult to clean the adsorption resin.
Standard of quality:
Item |
Specification |
Test result |
Assay ( HPLC) |
Chlorogenic Acid≥98% |
98.17% |
Appearance |
White Fine Powder |
Conformed |
Odor/Tast |
Characteristic |
Conformed |
Mesh |
80 mesh |
95% pass |
Chemical & physical control |
||
Loss on drying |
≤5.0% |
0．27 |
Ash content |
≤1.0% |
0．25% |
Solvents residue |
||
Heavy metals |
≤10ppm |
Conformed |
Pb |
≤2ppm |
Conformed |
As |
≤2ppm |
Conformed |
| Pesticides Residue | Negative |
Conformed |
Microbiological control |
||
Total Plate Count |
≤1000cfu/g |
Conformed |
Yeast & mold |
≤100cfu/g |
Conformed |
Salmonella |
Negative |
Conformed |
E.Coli |
Negative |
Conformed |
Conclusion |
Conform with specification. |
Product feature and application
1. Antihypertensive effect
The study found that Eucommia chlorogenic acid 98% has an unparalleled "two-way regulation" function on blood pressure. Studies suggest that its antihypertensive effect may be mainly related to lignans.
4. Anti-tumor effect
The research found that the anti-tumor mechanism of Eucommia ulmoides is mainly manifested in the following aspects: Eucommia ulmoides polysaccharides can induce tumor cell apoptosis to directly kill tumor cells; Eucommia ulmoides extracts can block the synthesis of nitrosamines and remove nitrite effect.
8. Anti-fatigue effect
Eucommia ulmoides extract can increase hormone levels in exhausted exercise rats, improve substance metabolism, extend exercise time, and enhance exercise capacity.
9. Other functions
In addition to the above-mentioned effects, Chlorogenic acid 98 or its extracts also have antibacterial, anti-inflammatory, sedative, antiemetic, weight loss, diuretic and gall bladder effects.
Application fie
ld: Eucommia ulmoides extract can be used as raw materials for injections, raw materials, health products, cosmetics, food additives.
Dosage forms: suppositories, lotions, injections, tablets, capsules, etc.
Safe dose:
Executive Standard: Chinese Pharmacopoeia Standard
Product storage: Store in a cool, dry place, away from light and high temperature.
http://www.nqqxpharma.com/
